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Post by miu on Aug 31, 2021 2:14:52 GMT -5
Dear DAVID,
Could you please let me know how to deel with the number of background when you calculate the P value in enrichment analysis focusing on specific hierarchy (ex. "GOTERM_MF_5").
For example, I submit 100 gene list and 1,000 background gene, does the number of background remain 1,000 in calculation of P value in enrichment analysis focusing on "GOTERM_MF_5"? Or, is the number of background replaced to "the total number of GOTERM_MF_5"s among 1,000 background gene in the case of above?
Best regards,
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Brad
DAVID Bioinformatics Team
Posts: 60
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Post by Brad on Sept 28, 2021 9:41:00 GMT -5
The list and background gene counts will be used including which genes are and are not annotated to any term as well as the particular term in GOTERM_MF_5. Please see the information about the calculation for further details. Regards, Brad
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