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Post by Forrest W on Jan 5, 2021 19:19:47 GMT -5
Hi, I have been using DAVID for several years to analyze sets of chicken (Gallus gallus) proteins. When I went to use DAVID today, it was only recognizing slightly more than half of the Uniprot accessions, even in protein sets where it previously recognized more than 90% of the accessions. Uniprot recently deleted many chicken accessions that it deemed redundant, but I was glad that DAVID continued to recognize the old accessions. I can find no evidence that the DAVID Knowledgebase was recently updated to the new Uniprot, so I am unsure if a database update is actually the problem. Either way, it would be useful if DAVID could continue to recognize past accessions, even after they have been archived on the resident databases. I now can't use DAVID for my older datasets as it is.
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Post by Forrest W on Jan 8, 2021 14:51:39 GMT -5
An update: DAVID recognized my protein list yesterday, so I assumed the problem had been fixed. Unfortunately it is back to recognizing only 186/297 proteins today.
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Brad
DAVID Bioinformatics Team
Posts: 67
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Post by Brad on Jan 8, 2021 15:04:28 GMT -5
The production DAVID Knowledgebase has not been updated recently although we are working on an update for an upcoming beta release.
DAVID has been experiencing intermittent database connection issues which we are currently trying to understand and resolve. I believe that your issue may be the result of this disconnect. The connection has currently been reestablished so I would expect that your list will be fully loaded at this time.
We will continue to work to resolve the issue permanently and we apologize for the inconvenience.
Regards, Brad
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