Post by DAVID user on Jul 21, 2020 15:14:29 GMT -5
I'm trying to do functional annotation for some camel genes. When I submit the list of uniprot_accession, it always gives me "You are either not sure which identifier type your list contains, or less than 80% of your list has mapped to your chosen identifier type. Please use the Gene Conversion Tool to determine the identifier type." For example, if I submit the list below, only 13 genes could be mapped and the rest 17 genes were unknown (same after gene accession conversion). But all of them are uniprot accession numbers. Some of the unknown ones have their GO annotation on Uniprot website (e.g. T0M9U1). Not sure why this happens. I'm new to the David website so just trying to learn. Thanks a lot for your help!
Last Edit: Jul 24, 2020 14:59:11 GMT -5 by DAVID user
Post by DAVID user on Jul 21, 2020 15:19:08 GMT -5
Thank you for including your ids and the screenshots. They are very useful for us to understand why this is occurring.
DAVID is currently using Entrez Gene Id as a central identifier. Unfortunately, if a mapping for a given Uniprot accession back to Entrez Gene id is not available from NCBI, Uniprot, Ensembl, etc, we are unable to include the accession in DAVID.
We apologize for the inconvenience and we are actively looking for other solutions to include more annotation into DAVID so your case is very helpful to us.
For now, we suggest using the first option (Continue to Submit the IDs That DAVID Could Map) after submitting your list of Uniprot accessions:
Last Edit: Jul 21, 2020 15:19:44 GMT -5 by DAVID user