Post by aeplatts on Jan 4, 2022 15:50:32 GMT -5
Hi,
This may be a variant of the high gene-list count question.
In our scenario we want to split a genome into exactly two parts and contrast the GO-terms of the genes in the two
fractions. One way to do this would be to set one fraction to be the foreground and the other the background
list, but the gene counts are too high I think.
I could just annotate each gene and count genes from fraction A and B in each GO, and then divide
by the number of genes in A and B. But I'm concerned about potential issues with how many GOs each gene
could map to and other gotchyas that DAVID handles. Is there a simple and correct way to do this?
AP
This may be a variant of the high gene-list count question.
In our scenario we want to split a genome into exactly two parts and contrast the GO-terms of the genes in the two
fractions. One way to do this would be to set one fraction to be the foreground and the other the background
list, but the gene counts are too high I think.
I could just annotate each gene and count genes from fraction A and B in each GO, and then divide
by the number of genes in A and B. But I'm concerned about potential issues with how many GOs each gene
could map to and other gotchyas that DAVID handles. Is there a simple and correct way to do this?
AP