I am doing a GO enrichment analysis on my proteomics results and the top rank category gives me a p-value of 0, which does not allow me to do the -log10 transition. I am wondering if there is any way that I can use to calculate the precise p-value.
It seems very odd that you would get a p-value of 0 in DAVID. You may want to check the download file which should have more precision to see if it is also 0. It would also be helpful if you could email us your gene list and the parameters that you chose in DAVID so that we may look into the situation further.