DAVID use with INTERPRO file

Hi everybody, 

I have an enrichment analysis to do linked to RNA-seq data with INTERPRO IDs. I have a list of genes with reads counts average and reads count average per gene length and INTERPRO IDs for each genes, and some have multiple ones. 

I used before to do GO enrichment using topGO on R. In this case I only have INTERPRO IDs and I found DAVID multiple times cited in articles using INTERPRO for gene set functional enrichement. 

Could you please help me to better understand how I can use DAVID for my purpose? 

I am studying non models organisms. So I will need to build a local DB of INTERPRO domains found within the proteins of the ref genomes of my species. Is it possible to do this with DAVID? 


Thank you in advance for your help :-)

Cheers